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KMID : 1094020180350040155
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Journal of Veterinary Clinics
2018 Volume.35 No. 4 p.155 ~ p.160
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Primary Splenic Paraganglioma in a Dog
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An Su-Jin
Moon Jong-Hyun
Hwang Tae-Sung
Lee Hee-Chun
Yu Do-Hyeon
Sur Jung-Hyang
Jung Dong-In
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Abstract
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A 6-year-old intact female Shih-tzu dog was referred due to anorexia. Physical examination, complete bloodcount, serum chemical analysis, radiography, and ultrasonography were evaluated. Physical examination andhematological analysis showed normal findings. Abdominal radiographs and ultrasound revealed well-defined massesin the spleen. Other abdominal organs showed no significant abnormalities. Tissue samples taken via sono-guided fineneedle aspiration of the splenic mass showed many bare nuclei, which were variable in size. Results of histopathologicaland immunohistochemical (IHC) analyses performed after splenectomy were consistent with paraganglioma. Based onthese findings, we diagnosed this patient with a paraganglioma of splenic origin. Two months after splenectomy,abdominal ultrasonography revealed a new neoplastic lesion in the liver. The clients refused further management andthe patient expired three months after initial diagnosis. Necropsy as well as histopathological and IHC examinationsof other systemic organs including the liver, adrenal gland, kidney, brain, urinary bladder, lung, aortic body, carotidbody, and pancreas were performed. The neoplastic tissue in the liver also demonstrated features of a paraganglioma,and there were no remarkable findings in all other organs.
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KEYWORD
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dog, immunohistochemistry(IHC), spleen, paraganglioma, chemodectoma
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